Tel: +39 081-5132163
  Email : info@avantech.it

Strumentazione Analitica

​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​Atomx XYZ​​​ – Automated VOC Sample Prep System

The Atomx XYZ is the second generation combined soil/water autosampler and purge and trap concentrator system in the Tekmar VOC product family. It is the only instrument of its kind to employ a unique automated methanol extraction feature for high level soils in accordance with USEPA Method 5035. Methanol rinsing, dilutions capability and three standard addition vessels all come standard on the Atomx XYZ. While priced competitively, the system offers unique features that cannot be found on any other sample prep system on the market today.​ (download here the brochure)

Applications and Industries 

VOC sampling and analysis are used in a wide range of applications in the following industries:

  • Environmental
  • Food and Beverage
  • Pharmaceutical
  • Flavor, Fragrance, and Packaging
  • Petrochemical

Methods 

  • USEPA 502.1, 502.2, 524.2, 524.3, 524.4, 503.1, 601, 602, 603, 624, 5030, 5035, 8010, 8015, 8020, 8021, 8030, 8240, 8260
  • ASTM and Standard Methods
  • Massachusetts VPH and GRO Methods

KEY FEATUERS

  • ​​​84-position vial tray with optional vial chiller to 4 °C
  • Reduced footprint by 13 cm (5”) compared to the previous generation Atomx
  • Reduction of the amount of water transferred to the GC by as much as 60% over previous models, due to the improved Moisture Control System
  • Reduction of potential leak sources due to a precision machined valve manifold block, ensuring a reliable and robust system
  • Faster trap cooling time through dedicated ducting
  • Re-designed software that is intuitive, user-friendly, touchscreen compatible and USB driven to be fully compatible with Windows 10
  • Use of Helium or Nitrogen due to the patented ​Electronic Mass Flow Controller (MFC). The MFC gives the ability to vary flow rates in different modes thus increasing sample throughput
  • Excellent desorption efficiency due to proprietary trapping material
  • Optional Guardian Foam Sensor and Eliminator for foaming sample types
  • Foam detection and prevention options, vial chilling and sparge vessel heater accessories all available​​
  admin   Gen 22, 2018     Commenti disabilitati su ​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​Atomx XYZ​​​ – Automated VOC Sample Prep System   Read More

FID TOWER PLUS

CARATTERISTICHE UNICHE Grazie al design salva-spazio, il FID TOWER Plus, con un’autonomia 5lt d’acqua demineralizzata tramite sistema interno di serbatoi, non necessita di taniche esterne. Un’unica alimentazione per entrambi gli strumenti (220v o 110V) La sezione Idrogeno è priva di manutenzione, grazie all’esclusivo dryer non riscaldato e alla semplice sostituzione del sacchetto deionizzante, senza attrezzi e senza spegnere lo strumento   Il generatore d’idrogeno ed aria FID TOWER PLUS utilizza la nuova e più recente tecnologia a membrana polimerica (PEM) per la produzione d’idrogeno puro. Ideale per l’utilizzo per rivelatori gas cromatografici quali: • FID / NPD / TCD • Gas reagente per: ELCD / HALL. Lo sviluppo verticale della FID TOWER PLUS ne permette il posizionamento sopra il banco da lavoro tra gli strumenti dato il suo spessore di soli 14 cm. Il generatore è provvisto di un sistema automatico di caricamento acqua deionizzata che garantisce all’utente una capienza di 5 litri di acqua demineralizzata. Il pratico sistema di sostituzione del sacchetto deionizzante semplifica notevolmente l’unica operazione di manutenzione consigliata senza la necessità di spegnere lo strumento. Il generatore . disponibile con flussi di produzione H2 sino a 600 cc/min con purezza sino a grado 7 e pressione di 11 bars. Nel sistema integrato anche il purificatore d’aria Zero capace di erogare sino a 5000 cc/min di Aria pura. Il sistema FID STATION PLUS è disponibile nella versione: • Generatore di H2 • Generatore di H2 + Generatore d’Aria nello stesso chassis e con le medesime dimensioni ridotte.

fid-tower-plus

 

CONTROLLO

Microprocessore Interfaccia di controllo, LCD touch screen con visualizzazione in tempo reale di: pressione erogata, qualità dell’acqua, autodiagnostica con allarmi rivelatori di perdite H2, livello e qualità dell’acqua. Massima silenziosità operativa. Semplicità d’uso: totale assenza di soluzioni caustiche e rigenerazione statica o dinamica dell’essicatore Accelerometro standard antischock Porta USB standard Display di controllo parametri idrogeno e manometro controllo Aria Zero facilmente visibili. Remote Software Control via RS232, USB, Intranet,  (anche per sistemi in Cascading) Automatic Stand-By mode indotto dal sensore di idrogeno (opzionale) in caso di perdite di H2 nel forno del GC.

 

CERTIFICAZIONI

CE, CSA, FCC

 

MIGLIORI RISULTATI CROMATOGRAFICI

L’idrogeno quale gas di trasporto è più veloce e sensibile rispetto al costoso elio. Notevole risparmio di tempo d’analisi senza perdita di risoluzione.

 

SICUREZZA

Il limitato volume interno inferiore a 50 ml rende il funzionamento sicuro in spazi dove l’utilizzo delle bombole è rischioso o proibitivo. L’utilizzo di comprovate tecnologie di sicurezza bloccano il sistema in caso di malfunzionamento o perdite. Un sensore opzionale è disponibile per l’installazione nel forno del gascromatografo per il monitoraggio continuo del valore di idrogeno in camera. La serie DBS Plus dispone di accelerometro standard in grado di bloccare il generatore qualora siano presenti forti scosse (es. terremoto)

 

RISPARMIO

L’uso del generatore d’idrogeno evita costosi impianti per il trasporto del gas dal bunker esterno all’utenza finale, oltre alla continua sostituzione di bombole per il successivo riempimento.

La doppia configurazione H2 o H2+Aria, disponibile in un solo strumento di dimensioni ridotte, consente di ottimizzare gli spazi ed i costi.

 

PRODUTTIVITA’ DEL LABORATORIO

Il continuo funzionamento h24 consente la massima produttività del laboratorio, evitando perdite di tempo nella sostituzione delle bombole e per la manutenzione del sistema essiccante.

 

SEMPLICITA’ DI MANUTENZIONE

L’unica manutenzione dello strumento è facilitata dal sistema di accesso al secchetto de-ionizzante permette una sostituzione dello stesso rapida e facile, senza necessità  di attrezzi o di spegnimento dello strumento

 

 

DIAGRAMMA

FID_TOWER_SCHEME

TABELLA DATI

DataChart_Tower
  admin   Ott 25, 2016     Commenti disabilitati su FID TOWER PLUS   Read More

CLAM 2000

The CLAM-2000 fully automated sample preparation module for LCMS is based on the extensive blood coagulation analyzer technology that Shimadzu has cultivated over many years. Simply place blood collection or other tubes in position and the system fully automates everything from pretreating blood or other samples for analysis to LCMS analysis. Consequently, the system is able to minimize human error and variability in sample pretreatment procedures. Therefore, it helps achieve a high-precision workflow for clinical research that is safer, faster, and simpler.

Seamless Integration of Sample Preparation and LC-MS/MS Analysis.

  • Simply place the blood collection tubes to be analyzed, necessary reagents, and specialized pretreatment vials into the CLAM-2000 which then performs all processes automatically.
  • Each sample is processed successively in parallel, to optimize instrument usage and sample throughput.
  • The CLAM-2000 frees up time spent by laboratory staff performing tedious sample preparation steps, thus increasing laboratory efficiency.

Thorough Precision Control of Analytical Results.

  • Easy to access software controlled management of reagents, calibration curves, control samples, and system maintenance ensures system performance and reliability.
  • Easy to interpret charts and figures alert users to decreasing reagent volumes or variable QC sample results.

Reduces Operator Errors and Enhances Laboratory Safety During Procedures.

  • Eliminates manual operations involving biological samples, such as dispensing. Not only does this improve reproducibility of data, but it minimizes user contact with biohazardous material.
  • Potentially infectious waste products are kept isolated inside the system. This allows such waste to be disposed of after the analysis is finished, according to the procedures specified for that laboratory.

Perform All Processes from Collection of Samples in the Blood Collection Tubes to Sample Pretreatment and Analysis Automatically

User-Friendly Experimental Design and Execution

Depending on the samples being analyzed, operations involve two simple steps – placing the blood collection tubes and reagents in the system and then requesting the desired sample analyses in the software. Using a liquid crystal touch panel display, the CLAM-2000 interface was designed to make LCMS sample preparation and analysis accessible to all users, regardless of the level of experience. The CLAM-2000 offers a next-generation workflow for routine LC-MS/MS analysis that helps ensure reliable and rapid operations.

Advanced options for displaying, reporting, and managing data results can be easily accessed through the CLAM-2000 software by linking to LabSolutions.
Note: An optional LCD screen can be installed for monitoring LCMS analysis.

Precise Control of Analytical Results

Improves Accuracy and Reproducibility of Analytical Data

Sample batches are easily created through a barcode reader or by direct entry to facilitate sample analysis. CLAM-2000 software ensures reliable results and continuous operation by tracking solvent levels, calibration curves, QC samples and instrument parameters. These measures help to ensure a routine analysis workflow that continues to provide high-quality results.

The Benefits of CLAM-2000 Automation on LC-MS/MS Workflows

Seamless Automation

The CLAM-2000 not only automates common steps in LC-MS/MS sample preparation protocols, but it delivers the sample to the LC autosampler for injection. Most often, sample preparation involves protein precipitation and derivatization and the CLAM-2000 provides all of the functions required to execute these critical steps.

Reduces Operator Errors

Once the samples and the filtration/collection vials are loaded into the sample carousel, users use a touch panel screen to queue the samples and order the methods. Once loaded, all steps are automatically performed including the LC-MS/MS analysis. Removing the operator from the process in effect removes operator error, thus increasing reproducibility.

Increased Laboratory Efficiency and Safety

Laboratory staff will no longer be tied to a bench, processing samples. Operators will simply need to load samples and reagents, create the batch and press start. Exposure to samples are minimized and all potentially hazardous waste is isolated inside the CLAM until it can be disposed of according to proper laboratory safety procedures.

CLAM-2000-LC-MS/MS Application Examples

Steroids

This analysis flow is an example of a simultaneous multicomponent analysis of steroids in serum using a fully automated preparative LCMS analysis system consisting of a Nexera X2 Ultra High Performance Liquid Chromatograph, LCMS-8060 Triple Quadrupole Mass Spectrometer, and CLAM-2000 fully automated sample preparation module for LCMS.

Pretreatment Conditions and Analysis Flow

Quantitative results of drug spiked into serum

CompoundsPolarityRange
(ng/mL)
r2QC samples concentration (ng/mL)Accuracy (%)%RSD (n=3)
LLOQMiddleULOQLLOQMiddleULOQLLOQMiddleULOQ
 Aldosterone+0.03 – 1.140.9970.030.461.1496.5102.0102.86.37.93.6
 Cortisol+1.51 –
320
0.99915.120.8320104.4100.498.61.60.50.7
 DHEAS+12.9 –
2750
0.99912.91792750104.3101.399.63.93.61.9
 Corticosterone+0.29 –
62
0.9980.294.0362101.8101.098.44.60.81.0
 11-Deoxycortisol+0.08 –
18
0.9970.081.1718103.0102.796.15.50.90.2
 Androstenedione+0.08 –
18
0.9990.081.1718116.599.1100.14.61.31.1
 Testosterone+0.03 –
7.2
0.9990.030.477.293.8101.4100.13.71.01.0
 17-OHP+0.12 –
26
0.9980.121.6926103.6103.399.66.21.61.8
 DHEA+0.31 –
65
0.9990.314.226593.198.199.06.53.96.5
 Progesterone+0.12 –
26.5
0.9990.121.7226.5103.3101.099.23.91.11.5
 Aldosterone (neg)0.03 –
1.14
0.9960.030.461.14115.097.397.46.67.58.0
 DHEAS (neg)12.9 –
444
0.99712.920.8444101.7103.099.72.11.27.1
  admin   Ott 25, 2016     Commenti disabilitati su CLAM 2000   Read More

GCMS-TQ8050

Enhanced Sensitivity Leads to New GC-MS/MS Possibilities

The GCMS-TQ8050 features a new highly efficient detector and three noise reduction technologies that enable femtogram-level quantitative analysis.
Also, the increased instrument robustness and safety provide dramatically improved reliability for ultra trace analysis.
A new detector with better amplification performance maximizes the benefits of the OFF-AXIS Ion Optics, which offers both high ion transmission performance and outstanding noise elimination performance. These state-of-the-art technologies enable the system to reliably detect ultra trace quantities of ions, down to the femtogram level, achieving the world’s highest*sensitivity levels.
* As of August 2016, according to a Shimadzu survey
In addition to high sensitivity, the system offers highly robust performance. The contamination-resistant ion source and the new detector with over five times longer service life ensure reliable, long-term analysis. An oil-free pump that can be operated for three years without maintenance is also available.
A new turbomolecular pump with higher evacuation performance achieves a superior vacuum state in the MS unit. This results in higher sensitivity and stability and helps improve analysis accuracy for ultra-trace concentration levels.
Using the ultra-fast analysis technology (UFsweeper) offered in existing models, the system can simultaneously analyze samples using multiple modes, such as high-speed scanning and scan/MRM modes.
The Smart MRM technology that optimizes sensitivity helps accurately create methods for ultra-trace analysis and ensures high sensitivity for MRM measurements. In addition, the enhanced accuracy control function provided by LabSolutions Insight software improves the reliability of analyzing data acquired from simultaneous multicomponent analysis of ultra-trace components.
  admin   Ott 25, 2016     Commenti disabilitati su GCMS-TQ8050   Read More

AA-6880

aa6880

Double-Beam Optics and Stable Hardware Achieve Superior Stability

The AA-6880 Series incorporates newly developed 3D double-beam optics.
The optical system has been designed to produce maximum performance for each measurement method through optimal adjustment of the light beam and light beam digital filter, and by using optical components that restrict light losses.

Advantages of the Double-Beam System

Long-term stability

The graph shows the results of measurements on 2 ppm copper (Cu) conducted over at least one hour. (The plot shows mean values for 11 repeated measurements.) Over the course of more than 600 measurements, the instrument achieved a relative standard deviation within 1%.

High sensitivity

The graph shows the direct measurement results for 0.1 ppm lead (Pb).

Support for Developing Analytical Conditions

Automatic gas flow rate optimization

Automatic searching for optimal fuel gas flow rate (Japanese Patent 2099886). It is important to determine the optimal gas flow rate for the flame when using an organic solvent or after changing the burner height. The AA-6880F Series automatically optimizes the gas flow rate by measuring the changes in absorbance between a blank and a standard sample. The difference between the two is displayed on the screen. The gas flow rate achieving the highest sensitivity is detected and this value is automatically set as the gas flow rate value.

Optional Autosampler Reduces Analysis Workload

Low carryover

Great care must be taken to avoid carryover during flame analysis. The new ASC-6880 autosampler rinses the nozzle at the rinsing port on the overflow mechanism after each sample measurement is complete. This ensures 10-4 max. carryover during measurements of multiple samples. The graph shows the results of consecutive analyses of 10 ppm, 20 ppm, and 50 ppm sodium (Na) standard solutions in the EMISSION mode. No carryover could be detected when measuring the 10 ppm standard sample immediately after measuring the 50 ppm Na standard sample.

Trace Sample Analysis Using Micro Sampling

Micro sampling

At least 1 mL (1000 μL) volume of a liquid sample is required for the continuous intake of sample during normal flame analysis. With micro sampling, however, approximately 50 to 90 μL of sample is injected in one shot into the flame and quantitation is based on the height and area of the peak signal obtained. This method offers the advantages listed below.

Advantages

  • Permits analysis of small sample volumes .
  • Multi-element analysis of small sample volumes .
  • No blockage of burner slot with samples having a high salt concentration .
  • Synchronized with the autosampler for auto-dilution measurements

* Synchronization with the autosampler requires the optional micro sampling kit.

Example of micro sampling analysis

Examples of the measured waveforms (overlaid) and calibration curve for micro sampling analysis are shown to the right. A 2-ppm Cu standard solution was prepared by auto-dilution using the autosampler. The autosampler can also be used to conduct dilution measurements of the sample. (Injection volume: 90 μL)

Achieves World-Class Lower Limits of Detection

Advances in optics and a new graphite furnace design achieve improved lower limits of detection for furnace analysis (comparison with previous Shimadzu models). This superb analysis performance is possible in all fields.

High-Performance Autosampler

  • Multi-element analysis of small sample voMix and inject up to four sample types (diluted solution, standard solution, sample, matrix modifier, etc.). (Unmixed samples can also be injected.)
  • Select a fluororesin tube or pipette tip as the injection nozzle.
  • Automatic dilution and re-analysis if the calibration curve concentration is exceeded.
Example of Automatic Dilution and Re-Analysis
Analysis of cadmium (Cd): The maximum concentration of the calibration curve has been set to 1ppb. At 1.8ppb, the sample of [003] has exceeded the maximum concentration. As a result, it has been automatically diluted by four times and re-measured.

High-Sensitivity Application Data (Analysis of Selenium (Se))

Independent control of the gas flow through the graphite tube during atomization achieves extremely high-sensitivity measurements. (Japanese Patent 2067563)

Measurement Example Showing High Sensitivity Analysis of 0 to 5 ppb selenium (Se): Sensitivity is adequate for 1 ppb measurements. (20 μL injected volume, Pd modifier, pyro-coated graphite tube)

Digital temperature control and electronic gas flow control enhance stability

Combination of a high-sensitivity optical sensor and unique digital temperature control technology achieves highly accurate temperature control in all temperature regions from drying to atomization. An electronic flow controller can precisely control the inner gas flow rate in 0.01 L/min units. These control techniques significantly enhance both the sensitivity and the data stability.

System Configuration Can Evolve with Your Needs

The AA-6880 Series can be upgraded by adding units to handle the analysis targets.

Analysis Sensitivities

Flame Selection

Comprehensive Safety Functions in Every System

Safety is an extremely important consideration for flame atomic absorption spectrophotometers using acetylene gas.
The AA-6880 Series instruments incorporate a comprehensive range of safety mechanisms, including gas leak detectors.

Safety Functions for Flame-Specification Instruments

  • Multimode automatic gas leak check
    The fuel gas pipes inside the instrument gas controller are automatically checked for gas leaks when the power is turned on and when the flame is extinguished. Should a gas leak be detected, a warning buzzer sounds and a warning is displayed on the screen.
  • Automatic flame ignition and extinguishing
    Flame ignition and extinguishing operations are extremely simple. The Air-C2H2 flame priority ignition mechanism prevents flashback.
  • Automatic gas shut-off by flame monitor
    After the ignition of an Air-C2H2 flame, the flame automatically switches to an N2O-C2H2 flame. If the C2H2 flow rate does not increase due to solenoid valve trouble, for example, switching to the support gas is disabled to prevent flashback.
  • Pressure monitor prevents flashback
  • Automatic gas shut-off by flame monitor
  • Sudden power interruption detection and re-ignition safety measures
  • Mechanism to prevent misuse of the burner
  • Drain tank level monitor

Safety Functions for Furnace-Specification Instruments

  • Cooling water flow rate monitor
  • Argon gas pressure monitor Furnace cooling check
  • Overcurrent protection unit (double-checked by circuit protector and optical sensor)
  • Design for preventing miss-ignition

Safety-Conscious Design

Flame-retardant materials
UL 94V-0-rated flame-retardant materials are used for the instrument external
covers and atomizer unit. This superior design pays due consideration to safety.Safe ignition switches
The switches perfectly fit finger contours and are positioned near the window.
To prevent inadvertent operation, both switches must be pressed simultaneously to start ignition.

The optimal background correction methods are installed as standard:
high-speed self-reversal method (SR method) and deuterium lamp method (D2 method).

These functions can correct for spectral interference in flame measurement.
Selecting the optimal background correction method for each sample ensures accurate and reliable analysis results.

The SR method is suitable for samples containing elements that cause problems with spectral interference, as shown in the table to the left.

  admin   Ott 25, 2016     Commenti disabilitati su AA-6880   Read More

ICPMS 2030

  • The first system in the industry to include functions for assisting with analytical method development and diagnostics.
  • Newly developed collision cell provides high sensitivity and low interference.
  • Unique system developed by Shimadzu results in the industry’s lowest running costs.

Features

Two Assistant Functions Simplify Analysis

The Development Assistant simplifies the process of developing analytical methods. The Diagnosis Assistant automatically diagnoses spectral interference. Together, they provide analytical results with exceptionally high reliability.

Designed for High Stability, High Sensitivity and low interference

The optimized internal structure including the newly-developed collision cell enables analysis at an excellent sensitivity with the minimum spectral interference.

Unique system developed by Shimadzu results in the industry’s lowest running costs.

In addition to lower running costs, the environmentally-friendly mini-torch plasma unit, developed by Shimadzu, minimizes the energy (electricity) consumed in producing and maintaining an argon plasma.
* As of February 2016, based on data obtained by Shimadzu

For Research Use Only. Not for use in diagnostic procedures.

Two Assistant Functions Simplify Analysis

The Development Assistant simplifies the process of developing analytical methods. The Diagnosis Assistant automatically diagnoses spectral interference. Together, they provide analytical results with exceptionally high reliability.

Development Assistant Function Ensures Analytical Methods
Can Be Developed with Confidence by Anyone.

Creating analytical methods for ICPMS-2030 analysis involves only selecting the measured and target elements, even for samples being analyzed for the first time. Then, based on the qualitative analysis data (for all mass numbers) from a representative sample, the Development Assistant automatically selects the optimal mass numbers and internal standard elements for the target measurement elements and automatically specifies the concentration range for calibration curve samples.

Obtain Reliable Results Quickly with the Diagnosis Assistant Function.

The Diagnosis Assistant automatically diagnoses spectral interference, based on data measured from all mass numbers. Even when using an already established method for routine analysis, the software analyzes data for any spectral interference to determine if a problem occurred.

Unique Combination Eco Mode/Mini-Torch Reduces Running Cost by Dramatically Reducing Gas Consumption

In addition to lower running costs, the environmentally-friendly mini-torch plasma unit, developed by Shimadzu, minimizes the energy (electricity) consumed in producing and maintaining an argon plasma.

Three Factors That Reduce Running Costs

Mini-Torch Plasma Unit

One of the highest costs associated with ICP-MS systems is the large quantity of argon gas they consume. However, Shimadzu’s proprietary mini-torch plasma system consumes two-thirds the argon gas (10 L/min) as conventional plasma torches. Consequently, one gas cylinder of argon (~7,800 liters) allows for approximately ten hours of continuous operation.

Eco Mode (5 L/min of Plasma)

During standby when Eco mode is active, the plasma gas flow and power are reduced to 5 L/min and 0.5 kW to minimize the required gas and electricity; however, analysis can be started immediately with no loss of productivity.

Low-Purity Argon Compatible

High-purity argon gas required by conventional systems is no longer necessary. Using less expensive argon gas (99.95%) over a three-year period can reduce costs by several tens-of-thousands of dollars.

Designed for High Stability and Low Running Costs

New High-Frequency Power Supply!

Shimadzu is the world’s first ICP manufacturer to develop an all-solid-state high-frequency power supply. Due to Shimadzu’s extensive experience, this free-running type high-frequency power supply unit offers the highest output stability. * As of December 2015, based on data obtained by Shimadzu

ICPMS-2030

More Compact Vacuum System!

The smaller three-stage split-flow turbomolecular pump is especially easy to maintain, maximizing up-time of the instrument.

Secondary Electron Multiplier Tube Detector!

The 9-digit dynamic range detector allows for measuring major components and trace components simultaneously with high sensitivity.

Lens System Minimizes Contamination!

Located behind the newly developed collision cell, the focusing lens improves ion transmission efficiency and elimination of light emission from the plasma. * Light emission removal is especially important when combining with Laser Ablation systems.

Newly Developed Collision Cell!

The newly developed collision cell achieves superior sensitivity by providing highly efficient molecular ion removal and high elemental ion transmission using only helium gas.

Newly Designed Interface!

The newly designed interface allows for easy maintainability. All parts can be removed and installed without the need for tools, which helps minimize downtime associated with cleaning and servicing.

High Stability and Low Running Costs

Shimadzu’s Proprietary Mini-Torch Plasma System
Based on Shimadzu’s extensive experience developing ICP emission spectrometers, Shimadzu’s independently-developed mini-torch unit offers unrivaled performance and savings. One of the highest costs associated with ICP-MS systems is the large quantity of argon gas they consume. However, Shimadzu’s proprietary mini-torch plasma system consumes two-thirds the argon gas (10 L/min) as conventional plasma torches. Furthermore, during standby when Eco mode is active, the plasma gas flow and power are reduced to 5 L/min and 0.5 kW to minimize the required gas and electricity; however, analysis can be started immediately with no loss of productivity.

Easy-to-Maintain Sample Injection System

Cyclone Chamber Cooled by a Peltier Element
The sample injection system features an electronically-cooled cyclone chamber utilizing a highly efficient coaxial nebulizer and unique overflow drain design. This design combines highly efficient aerosol production while reducing carryover to maximize sensitivity and throughput.

Environmental, Drinking Water, and Wastewater Analysis

Natural resources such as rivers, oceans, and soil are limited and we all share an obligation to preserve them for our future generations. In the world we live in today, we continue to place a burden on those resources through such practices as industrial manufacturing. It is essential that we preserve and protect our environment and our resources through reuse, recycling resources and reducing pollution. These can only be accomplished through monitoring by conducting massive amounts of measurements. To this end, Shimadzu provides a simple and accurate means of measuring samples so that recycling processes and manufacturing processes can be managed properly and responsibly.
Analytical Results of River Water
Element
Japanese Water
Supply Act Standard
(μg/L)
EPA Max. Limit Value
for Drinking Water
(μg/L)
Method Detection
Limit
(μg/L)
Samples:JSAC0301-3Samples::JSAC0302-3
Quantitation
Value
Certified
Value
Quantitation
Value
Certified
Value
Unit::μg/L
Al2002000.0091615±166.966±1
As100.0030.200.20±0.015.295.2±0.1
B10000.28.528.2±0.358.059±1
Ba700**20000.0010.550.53±0.010.550.52±0.01
Cd350.0060.00180.0018
(Reference value)
0.9911.00±0.02
Cr6+501000.070.170.16±0.0110.010.0±0.2
Cu100013000.090.40.37±0.0310.09.9±0.1
Fe3003000.016.56.4±0.258.558±1
Mn5050***0.010.210.20±0.015.35.1±0.1
Mo70**0.0040.300.290±0.0040.300.290±0.004
Ni10*0.0099.639.5±0.3
Pb10150.00050.0050.007
(Reference value)
9.689.9±0.2
Se0.070.20.08
(Reference value)
4.955.0±0.2
Zn10005000***0.020.170.17±0.0410.59.8±0.2
Unit:mg/L
K0.480.47±0.020.480.48±0.02
Na2004.534.34±0.074.474.32±0.07
MgHardness
:300
3.373.34±0.073.343.32±0.06
Ca250***13.213.0±0.213.113.0±0.1

*: Target setting item, **: Required test item, ***: National Secondary Drinking Water Regulations

Pharmaceuticals/Pharmacopoeia

Many of the pharmaceuticals, food products, and other products we encounter can contain harmful elements, either introduced from natural sources or artificially through manufacturing processes. ICP-MS systems are able to quickly measure harmful elements with high sensitivity, making them ideal for monitoring such substances and ensuring the safety and security of pharmaceuticals, foods, and other products. Additionally, pharmaceuticals must satisfy the allowable limits specified by ICH Q3D guidelines, where the measurement methods used are specified in the pharmacopoeia of respective countries. The system must also be compliant with quality control standards specified by the FDA and Japanese Ministry of Health, Labor and Welfare.

Analytical Results of Tablet

ElementOral Drug,
PDE μg/day
Max. Allowable Concentration μg/gMeasurement Value in Tablet μg/gEquivalent Tablet Dose
DL(3σ)μg/g
Recovery Rate %
Cd50.5N.D.0.0005103
Pb50.50.0090.002103
As151.5N.D.0.006110
Hg303N.D.0.000298
Co5050.0040.00004100
V10010N.D.0.01110
Ni200200.660.003110
Tl80.8N.D.0.0000298
Au10010N.D.0.0003104
Pd10010N.D.0.000299

Food Products/Agriculture

We rely on foods to provide necessary elements and minerals required for supporting life. However, if food contains hazardous elements, they can be harmful to our health. Therefore, analyzing food has become increasingly important in recent years for ensuring the safety of food. One example of this is powdered infant formula which is made with a healthy balance of minerals necessary for infant growth. Regulatory requirements specify the amounts of calcium (Ca), iron (Fe), copper (Cu), and other essential minerals and while limiting hazardous elements like arsenic (As), which has detrimental effects on child development. The ICP-MS is able to quickly measure a wide variety of elements in powdered milk products and other foods, including raw ingredient and finished products.

Analytical Results of Powdered Milk

UnitNMIJ Certification ValueAnalytical Value (in the powder)Detection Limit in PowderDetection Limit in Measured Solution (DL: 3σ) μg/L
Cumg/kg4.664.790.005
Mn0.9310.9260.0002
Mo0.2230.2110.0005
Sr5.885.660.00004
Zn41.341.50.003
Cdμg/kgN.D.0.05103
CrN.D.0.3103
PbN.D.0.195
As(2.1)2.50.5105

LC-ICP-MS

The environment, pharmaceuticals, food and other products can contain elements in different chemical form or oxidation states. Speciation of these is sometimes required.

By combining different analytical techniques like LC-ICP-MS, speciation of chemical forms can be achieved with high sensitivity. This is accomplished by connecting the ICPMS-2030 in-line with an LC (Shimadzu Prominence Inert LC) system. LabSolutions ICPMS TRM (time-resolved measurement) software controls the LC (Shimadzu Prominence Inert LC System) from the ICPMS-2030, allowing for one smooth platform that automatically detects and measures analyte peaks.

LabSolutions CS/DB for ICPMS-2030 Supports Laboratory
Networking and FDA 21 CFR Part 11 Compliance.

LabSolutions CS/DB ICPMS provides compliance for regulations concerning electronic record keeping and electronic signatures required by FDA 21 CFR Part 11 and other regulations stipulated by Japan’s Ministry of Health, Labor and Welfare (ERES regulations). Additionally, since the software supports laboratory networking, analytical results from a broad variety of analytical instruments used in the laboratory, including LC, LCMS, GC, GCMS, UV, FTIR, RF, EDX, TOC, and PPSQ, can be managed centrally from a server.

Data Management Methods Available Depending on the System

Network System: LabSolutions CS (coming soon)

LabSolutions CS can freely access all instruments on the analytical network, so that all analytical data is managed on the network server and the data can be loaded to any computer connected to the network. This is especially recommended for customers that have many users and want to manage data on a server together with LC, GC, FTIR, UV, RF, EDX, TOC, PPSQ, and other data for ER/ES compliance.

Standalone Database System: LabSolutions DB ICPMS (option)

This configuration does not require a network connection and is ideal for customers that want to manage all data on one computer for ER/ES compliance only for a standalone system.

System Contents

Network system LabSolutions CSLabSolutions ICPMS, LabSolution CS Connection Kit, LabSolutions CS
 Standalone database system LabSolutions DB ICPMS LabSolutions ICPMS, LabSolution DB Connection Kit

Autosampler AS-10
(For automatic analysis of 60 samples)

Autosampler AS-10

Autosampler AS-10

Multiple samples can be analyzed successively. The turntable results in a short path length for sample injection, which can reduce the rinse time.

Vials: 60 15- mL vials
8 50-mL vials
Size: W290 × D508 × H300 mm (excluding arm)
Power supply: Single-phase 100 V, 50/60 Hz, 100 VA
Note: Requires separate power cord (P/N S071-60821-08).
Note: An additional rinsing port is optional (There is no automatic solvent supply).
Rinsing Port Expansion Kit for AS-10.

Autosampler ASX-26
(For simultaneous analysis of 120 samples)

ASX-26 Autosampler

ASX-26 Autosampler

Vials:
10 50-mL vials (standard samples) or 120 14-mL vials
80 20-mL vials (rack sold separately)
42 50-mL vials (rack sold separately)
Size: W330 × D508 × H250 mm
(main unit/excluding sample probe unit)
W90 × D180 × H60 mm
(rough dimensions of power supply unit)
Power supply: 100 V AC ± 10 %, 200 VA, 50/60Hz
Weight: 8.4 kg (main unit)
Note: Requires a separate connection kit.

Autosampler ASX-520
(For simultaneous analysis of 240 samples)

Autosampler ASX-520

Autosampler ASX-520

Vials: 10 50-mL vials (standard samples) or 240 14-mL vials 160 20-mL vials (rack sold separately) 84 50-mL vials (rack sold separately) Size: W520 × D482 × H250 mm (main unit/excluding sample probe unit) W90 × D180 × H60 mm (rough dimensions of power supply unit) Power supply: 100 V AC ± 10 %, 200 VA, 50/60Hz Weight: 10.5 kg (main unit) Note: Requires a separate connection kit (P/N S211-94010-41).

HVG-1 Hydride Generator
For high-sensitivity analysis of As, Se, and Sb

HVG-1 Hydride Generator

HVG-1 Hydride Generator

This unit uses nascent hydrogen generated from decomposition of sodium borohydride to vaporize elements in samples by reduction and then introduce only the gas phase into the plasma. This enables measurements with about 50 times higher sensitivity.
Note: Requires a separate HVG-ICPMS connection kit and liquid waste pump

Cooling Water Circulator Set

Cooling Water Circulator Set

Cooling Water Circulator Set

Size: W377 × D500 × H615 mm
Power supply: Single-phase 200 V, 50/60 Hz, 2 kVA
Weight: 43 kgNote: Used to cool the main unit.
Note: Requires a separate chiller connection kit (P/N S211-93827-41).
Note: Requires tetoron braided hoses (P/N S018-31509) for coolant water supply and drain. Order in meter units for the overall length.

LC Connection Kit

This kit is used to connect ICPMS to an LC system (Prominence inert LC System).
Note: Requires LabSolutions ICPMS TRM (software) (P/N S211-49200-91) for LC Connection Kit

Automatic Internal Standard Addition Kit

This kit is used for in-line mixing of measurement sample and internal standard solutions and introducing the mixtures into the ICP system.

HFS-5 Hydrofluoric Acid Sample Injection System

This system includes a torch, chamber, extension tube, nebulizer, drain, and their corresponding accessory parts. If purchasing a new system, order this kit and an S2 orifice assembly. Used to directly inject samples that contain hydrofluoric acid. The nebulizer, chamber, and drain system are made using fluoropolymer materials and the injector unit on the torch is made using alumina.

Organic Solvent Injection System

To introduce organic solvents, a mixture of argon and oxygen gases (70% Ar and 30% O2) is injected into the interface unit to prevent precipitation of carbon (C) by the organic solvent. This system includes a Quadruple Torch for Organic Solvents, ICPMS, drain, and their corresponding accessory parts.

Laser Ablation Connection Kit

This connection kit is compatible with ESI NWR-213 laser ablation systems.

Tap Water Connection Kit

This is required if using tap water to cool the main ICPMS-2030 unit. Note: Requires a separate coupler set for tap water connection.

Exhaust Duct Connection Adapter

Noise Reduction Box for Rotary Pumps

Note: Requires Noise Reduction Box Connection Kit for Noise Reduction Box for Rotary Pumps.
  admin   Ott 25, 2016     Commenti disabilitati su ICPMS 2030   Read More

EDX-7000/8000

The Energy Dispersive X-ray Fluorescence Spectrometer EDX-7000/8000 measures the energy (keV) and intensity of the generated fluorescent X-rays to determine the type and content of the elements comprising a sample. It is applied for non-destructive elemental analysis of solid, powder, and liquid samples. It is widely used by electronics and automobile manufacturers around the world.

Principle and Features of X-ray Fluorescence Spectrometry

 

 

Principle of Fluorescent X-ray Generation

When a sample is irradiated with X-rays from an X-ray tube, the atoms in the sample generate unique X-rays that are emitted from the sample. Such X-rays are known as “fluorescent X-rays” and they have a unique wavelength and energy that is characteristic of each element that generates them. Consequently, qualitative analysis can be performed by investigating the wavelengths of the X-rays. As the fluorescent X-ray intensity is a function of the concentration, quantitative analysis is also possible by measuring the amount of X-rays at the wavelength specific to each element.

 

Supports Various Applications in Many Fields

■ Electrical/electronic materials

  • RoHS and halogen screening
  • Thin-film analysis for semiconductors, discs, liquid crystals, and solar cells

■ Automobiles and machinery

  • ELV hazardous element screening
  • Composition analysis, plating thickness measurement, and chemical conversion coating film weight measurement for machine parts

■ Ferrous/non-ferrous metals

  • Main component analysis and impurity analysis of raw materials, alloys, solder, and precious metals
  • Composition analysis of slag

■ Mining

  • Grade analysis for mineral processing

■ Ceramics

  • Analysis of ceramics, cement, glass, bricks, and clay

■ Oil and petrochemicals

  • Analysis of sulfur in oil
  • Analysis of additive elements and mixed elements in lubricating oil
 

■ Chemicals

  • Analysis of products and organic/inorganic raw materials
  • Analysis of catalysts, pigments, paints, rubber, and plastics

■ Environment

  • Analysis of soil, effluent, combustion ash, filters, and fine particulate matter

■ Pharmaceuticals

  • Analysis of residual catalyst during synthesis
  • Analysis of impurities and foreign matter in active pharmaceutical ingredients

■ Agriculture and foods

  • Analysis of soil, fertilizer, and plants
  • Analysis of raw ingredients, control of added elements, and analysis of foreign matter in foods

■ Other

  • Composition analysis of archeological samples and precious stones, analysis of toxic heavy metals in toys and everyday goods

Functional Design

Large Sample Chamber with Small Footprint

Installed width is 20% smaller than the previous instrument due to its compact body size. The EDX-7000/8000 can accommodate samples up to a maximum size of W300 x D275 x approx. H100 mm.

High-Visibility LED Lamp

When X-rays are generated, an X-ray indicator at the rear of the instrument and an X-RAYS ON lamp at the front turn on, so that the instrument status can be monitored even from a distance.

 

PCEDX Navi Software Allows Easy Operation from the Start

PCEDX Navi software is designed to simplify X-ray fluorescence spectrometry for beginners, while providing the feature set and capabilities demanded by more experienced users. The straightforward user interface offers intuitive operation and provides a convenient operating environment for beginners and experts alike.

Simple Screen Layout

Sample image display, analysis conditions selection, and sample name input on the same screen.

Collimator Switching from the Measurement Screen

Change the collimator diameter while observing the sample image. The selected diameter is indicated by a yellow circle.

Automatic Storage of Sample Images

The sample image is loaded automatically when the measurement starts. Sample images are saved with a link to the data file.

 

 

 

Once the measurement is complete, the element names, concentrations, 3σ (measurement variance) are displayed, together with the sample image, in an easy-to-understand layout. Display the result list and individual report with a single mouse click.

Measurement Setup Screen Using the Turret (sample positioning screen)

Support for Continuous Measurements

PCEDX Navi supports measurements using the optional turret. Switch between the sample image screen and sample positi

  admin   Feb 19, 2016     Commenti disabilitati su EDX-7000/8000   Read More

Comprehensive GCxGC System

Comprehensive GC-MS (GCxGC-MS) System is a powerful technique that provides two-dimensional chromatography data acquisition capability.

 

Applications

Shimadzu’s Comprehensive GC-MS (GCxGC-MS) System is suited for a variety of applications, including analysis of complex matrices such as a natural products that are hard analyze by conventional GC or GC-MS, and grouping analysis based on two-dimensional chromatograph patterns.

Application Examples:

Food, Flavor & Fragrance, Environment, Petrochemical etc,

Features

Separation of Overlapping Peaks

Peaks with similar boiling points that could not be separated adequately with one-dimensional chromatography can now be separated based on differences in polarity. This allows analysis of components that previously were difficult to separate in samples with complex matrices.

 

 

Image Patterns Show Compound Structure

GCxGC provides image patterns that can be correlated to compound structure; this capability is especially useful for grouping analysis of mixtures containing many components.

Analysis of Diesel Oil

The image shows patterns that indicate the number of benzene rings and number of carbons.

 

Comprehensive chromatography will be contains enormous peaks. To certainly detect these peaks, UFMS (Ultra Fast Mass Spectrometry) must be need. Shimadzu’s UFMS technologies, which minimize sensitivity losses even at faster scan speeds, can detect these peaks.

 

  admin   Feb 19, 2016     Commenti disabilitati su Comprehensive GCxGC System   Read More

TOX.I.S.

HPLC/PDA Solution for identification of drugs in body fluids

Toxicological analysis of body fluids is an important task whenever acute intoxications, abuse of drugs, or consumption of illicit drugs needs to be identified. Those analyses always require a lot of effort as a most universal sample pretreatment and identification method are called and has to be done as much as possible

automated and fast. Prominence HPLC system with photodiodearray detection configured in a special solution system offer an identification based on retention time and the UV spectra of the component which is sufficient in most cases where toxic relevant concentrations are detected.

The system is based on common hardware modules using a special column switching procedure to enable sample pretreatment for serum and urine samples with a cleaning and rinsing step, transfer the sample onto the analytical columns and separation. Column selection valves for the analytical columns make it

possible to use the system also for other methods such as therapeutic drug monitoring. Detection and Identification are done with photodiodearray detector and library search and matches with UV spectra libraries.

Highlights

·         Based on prominence hardware modules and LabSolutions software

·         Simple sample preparation

·         Patented column switching and online extraction procedure

·         Automated identification based on UV spectra and relative retention time

  admin   Feb 14, 2016     Commenti disabilitati su TOX.I.S.   Read More

GCMS-TQ8040

The Shimadzu GCMS-TQ8040 is the first triple quadrupole with Smart Productivity for high efficiency sample throughput, Smart Operation for quick and easy method development, and Smart Performance for low detection limits and Scan/MRM. These 3 smart technologies contribute to Smart MRM, and provide the most accurate, cost effective, and easy-to-use triple quadrupole GCMS you have ever imagined.

 

 

Smart Productivity

This new firmware protocol enables MRM analysis with up to 32,768 transitions in a single analysis. A simultaneous analysis can be performed with a conventionally difficult number of components, dramatically increasing productivity.

Smart Operation

GC-MS/MS analysis requires multiple settings that can be confusing to the average operator. With Smart MRM, the GCMS-TQ8040 software sets the analytical conditions automatically, making method development painless, fast, and easy.

Smart Performance

The exceptionally efficient ion source and collision cell provide low detection limits. High speed scanning control (Advanced Scanning Speed Protocol, or ASSP) and simultaneous Scan/MRM analysis mode provides high quality library searchable fragmentation spectra, and accurate low-level quantitative data in a single analysis.

  admin   Feb 13, 2016     Commenti disabilitati su GCMS-TQ8040   Read More